Accutane (Isotretinoin)

Accutane it is used at treatment of serious forms of nodular-cystic acne at patients after ineffective treatment by other medicines, including antibiotics.

You should take Accutane twice a day during meal. Swallow a capsule with water, milk, or any other non-alcoholic drink. Observe prescriptions of your attending physician.

The dosage is prescribed by the attending physician depending on reaction of organism on Accutane. Depending on efficacy of treatment the dosage can be enlarged or reduced. In case of fast positive reaction of an organism to treatment with Accutane, it is possible to stop intake of the drug before the terminal of the prescribed course.

After the ending of course of treatment with Accutane, it is necessary to make a 2-month's rest. If after 2 months acne still have not passed, the treating doctor can prescribe second course of Accutane.

Alcohol intake is not recommended during treatment with Accutane.

Accutane is one of forms of vitamin A. It reduces quantity of the dermal fat produced by sebaceous glands, and also accelerates natural neogenesis of a skin.

Take a medicine as soon as remember. In a case if time of the next reception of a drug already approaches, it is not necessary to take the missed dose. It is necessary to wait for the next intake of a drug. Do not take a double dose of a medicine.

It is necessary to store Accutane at temperature of 77 degrees by Farenheit (25 degrees C). Short storage is allowed at temperature of 59-86 degrees by Farenheit (15 - 30 degrees C). Store Accutane in protected from high temperature, humidity, and light place out of reach of children.

In case:

• you have an allergy to any component of Accutane;
• you plan to become pregnant, you are pregnant;
• you are breast-feeding.

• Do not donate blood during intake of Accutane and within 1 month after the terminal of treatment by Accutane.
• Do not take alcohol, taking Accutane.
• Deterioration of acne can be observed during the first part of course of treatment. It is not a cause to stop treatment.
• For prevention of dryness and fractures on lips you may use wetting cream.
• Do not do and do not plan any cosmetic procedures for a skin during treatment by Accutane and within at least 6 months after the terminal of course of treatment.
• Accutane can cause the hyper-sensitivity to the sun. Avoid long stay on the sun, ultraviolet lamps, do not use sun decks while you do not know how your skin reacts on Accutane. Use a sun-protection cream or wear protective clothes in a case if you plan to be outside during a long span
• Contraceptive tablets (Progestinum) which do not contain an estrogen, can react not so effectively during treatment by Accutane.
• Accutane can affect on Saccharum in a blood at sick of diabetes. Check Saccharum level in a blood and consult with the attending physician for definition of an optimum dose of Accutane.

Inform your doctor if any of these most common side effects persist or become bothersome:

• abnormal hair growth; abnormal skin sensations; bleeding and redness or swelling of the gums; changes in menstrual flow; chapped lips; decreased tolerance to contact lenses; dizziness; dry eyes and mouth; dry nose that may lead to nosebleeds; dry or peeling skin; fatigue; flushing; general body discomfort; hair thinning; headache; itching; lack of energy; nervousness; respiratory tract infection; sleeplessness; sweating; temporary worsening of acne; voice changes.

• severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre, aggressive, or violent behaviour; bowel pain; chest pain or pounding in the chest; dark urine; depression; difficult or painful swallowing; difficulty moving; excessive thirst or urination; fainting; fast heartbeat; fever; fractured or weak bones; hearing problems or ringing in the ears; increased pressure in the brain (pressure in the eye; nausea; vision changes; vomiting); joint or back pain; leg swelling; muscle weakness with or without pain; nausea; new or worsening heartburn; rectal bleeding; red patches or bruises on the legs; shortness of breath; seizures; severe birth defects; severe diarrhoeia; severe headache; skin infection; slurred speech; stomach pain or tenderness; stroke; stunted growth in children; sun sensitivity; swelling of the pancreas (fever; increased heartbeat; nausea; stomach tenderness; vomiting); swollen glands; thoughts of suicide; tightness in the lungs; vision changes; vomiting; weakness; yellowing of the skin or eyes.

Accutane is to be used only by the patient for whom it is prescribed. Do not share it with other people.